CRISPR/Cas9 Mini Model

Give your students a hands-on exploration of the next generation in genetic engineering! We are thrilled to be able to offer an affordable version of the 3D-printed Cas9 component of the CRISPR gene editing technology.

Jennifer Doudna, PhD, Professor at UC-Berkeley and Executive Director of the Innovative Genomics Initiative (IGI), is one of the pioneers of the CRISPR/Cas9 technique, which allows researchers to make specific changes to the genetic code of cells and organisms. 3D Molecular Designs designed and built the model for Dr. Doudna with Jacob Corn, PhD, Scientific Director of the IGI. The front segment of the surface model (white) detaches, allowing students a closer look at the guide RNA (orange) and two strands of DNA (light blue and dark blue) inside. The green section is the Protospacer Adjacent Motif, a specific sequence of 3-5 DNA nucleotides known as the PAM sequence. The PAM sequence must be present in double-stranded DNA in order for the cas9 protein to cut the DNA properly.

​The 5'' model is made of plaster by 3-D printing and should be handled with care. It will break if dropped, held tightly or handled roughly. The 11'' nylon model is more resilient but will break if held tightly or handled roughly. It is a custom PDB file.

CRISPR/Cas9 Gallery

5" Magnet-Docked Plaster CRISPR/Cas9 Mini Model


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CRISPR/Cas9 Mini Model Animations and Videos

Jennifer Doudna, PhD, explains the CRISPR/Cas9 gene editing technique. One of the technique's pioneers, Dr. Doudna is Executive Director of IGI and Professor at UC Berkeley.

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Molecule of the Month on CRISPR/Cas9

The Molecule of the Month by scientist, author and artist Dr. David Goodsell includes an introduction to the structure and function of the chosen molecule and a discussion of its relevance to human health and welfare. Molecule of the Month articles are frequently referred to by teachers, students and researchers.

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Product Details

 

Grade Level

Middle School
High School

College

Warnings

Choking Hazard
Science Education Product

List Price

5” Plaster Model
     $246 (CC9MM)

11” Nylon Model
     $1,450 (NCC9M)

This product is not available for shipping outside the U.S. and Canada.

Teacher Tip

Always have your students use plaster models over a table to minimize breakage. Simple breaks can usually be repaired with super-glue.

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