This 3-D structure shows the 2 subunits of the bacterial ribosome (30S and 50S) in the functional 70S ribosome. In the bound 70S conformation, the 3’-ends of the tRNAs are immediately adjacent to the catalytic adenosine in the large subunit. Different RNA domains are displayed in spacefill format and are many different colors (magenta, yellow, light green, cyan, gray, dark blue, and red-orange). Ribosomal proteins are displayed in spacefill format and are white. Each of the 3 tRNAs are displayed in spacefill format and are different shades of green.
Single-stranded mRNA feeds into the ribosome complex, where each 3-nucleotide codon is matched to its tRNA anticodon, and those corresponding amino acids are joined together into a peptide chain. The 2009 Nobel Prize in Chemistry was shared among Venkatraman Ramakrishnan, Thomas Steitz, and Ada Yonath. All 3 had a part in determining the structure and function of the ribosome.
The physical models of 3DMD’s individual 30S and 50S subunits cannot be assembled into the 70S complex, due to the static nature of the physical models.
This 4'' model is made of plaster by rapid prototyping and should be handled with care. Mini models will break if dropped, held tightly or handled roughly. Its PDB file is 2WDK.pdb.