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Don’t just tell your students about triplet codons, reading frames, or introns and exons. Let them discover these eukaryotic gene features as they explore the Map of the Human ß-Globin Gene©.
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Find information about the contents of your Map of the Human ß-Globin Gene©.
Bioinformatics is a computer-based discipline that focuses on the information DNA encodes. Bioinformatics software consists of various algorithms that sift through incredibly long sequences of nucleotides, searching for patterns that allow us to identify genes and deduce the amino acid sequence of the encoded proteins. The 3DMD β-Globin Gene Exercise© focuses on DNA from the information perspective.
A summary of the Human β-globin gene.
The β-Globin Gene Exercise© serves as an example of how we can encourage our students to ask thoughtful questions. Our approach is to challenge students with a specific task — in this case finding the β-globin gene — in the absence of the explanations that normally precede an exercise such as this.
The Teacher’s Map features highlighted reading frames and mutation sites.
Using the Map of the Human ß-Globin Gene©, your students will find the nucleotide sequence in the DNA that encodes the amino acid sequence of the β-globin protein, and highlight both the nucleotide sequence and the corresponding amino acid sequence on their student maps.
Extension activities for motivated students who seem to be interested in bioinformatics.
Connections to: A Framework for K-12 Science Education Practices, Crosscutting Concepts, and Core Ideas
Middle School High School College
2-4
Science Education Product
1 Student 1 Teacher Map $40 (BGGM-01S-01T) 3 Student 1 Teacher Map $60 (BGGM-03S-01T) 12 Student 1 Teacher Map $162 (BGGM-12S-01T)
To extend the life of your maps, gently remove the highlighter marks immediately following each use.
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