Amino Acid Starter Kit©

Enzymes in Action Kit©

Teachers who use our Amino Acid Starter Kit© say their students love the kit’s captivating mini toobers and they refer back to the activities throughout the year. Students explore the primary, secondary and tertiary structure of proteins. They learn the chemical properties and atomic structure of the 20 amino acid side chains and gain a basic knowledge of protein folding before discovering the importance of secondary structure and active sites. LEARN MORE

Take your students beyond the simple lock-and-key concept of enzyme action with this
dynamic, multifunctional kit. Color-coded foam pieces represent enzymes, a variety of
substrates and inhibitors. Students discover the specificity of substrate binding, how enzymes catalyze either catabolic or anabolic reactions and the effect of various inhibitors on enzyme action LEARN MORE

 Protein Student Modeling Pack©

Insulin mRNA to Protein Kit©

Students individually explore proteins and enzymes with hands-on models and digital activities. LEARN MORE

Students explore how mRNA is translated by the ribosome into a precursor form of insulin, and then how the precursor is processed to create the final, functional protein. After using the kit’s bioinformatics map to determine the nucleotide sequence that encodes the amino acid sequence of insulin, they fold a physical model of the 3D protein structure of insulin. LEARN MORE

ß-Globin Folding Kit©

Substrate Specificity Kit©

ß-globin becomes real in students’ hands as they fold mini toober fragments into a 3D protein model of ß-globin. Using folding maps to mark selected amino acids (primary structure) and alpha helices (secondary structure), small teams of students fold the protein into its 3-D tertiary structure; assemble the 3 fragments together to form the ß-globin protein; and add the heme group with an iron atom and O2 and explore how a single mutation causes sickle cell anemia. LEARN MORE

Help your students achieve that "aha moment" with this simple but elegant kit that demonstrates the highly-specific interaction between a substrate and an enzyme. Students use color-coded functional groups to construct a substrate and examine its chemical properties, use a mini toober to engineer an enzyme active site specific to the substrate constructed, explore different types of specificity including stereochemical specificity and absolute specificity, and discover how subtle changes in enzyme structure can have a significant impact on substrate binding in the active site. LEARN MORE