Synapse Construction Kit©

Synapse Construction Kit©Engage your classroom with hands-on modeling of neuronal communication! Students can use the colorful foam pieces in the Synapse Construction Kit© to:

  • Discover how the resting potential of a neuron is established.
  • Demonstrate the propagation of an action potential down an axon.
  • Simulate the action of the sodium-potassium pump in resetting the resting potential.
  • Explore the effects of neurotransmitters acetylcholine, dopamine and GABA on a post synaptic neuron.
  • Model cholinergic, dopaminergic and GABAergic synapses.
  • Compare and contrast metabotropic and ionotropic receptors.
  • Analyze the impact of various substances such as nicotine, cocaine, sarin gas and propofol on neuronal signaling.
  • And much more!


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Kit Contents

Synapse Construction Kit© 1-Group
Membranes 22
Synaptotagmin 1
SNAP/SNARE Proteins 2
Toxins 2
Gated Sodium Channels 4
Potassium Leak Channels 4
Gated Potassium Channels 4
Gated Calcium Channel 1
G-Protein Coupled Receptor 1
Transport Proteins 2
Sodium/Potassium Pumps 2
Acetylcholine Receptor 1
GABA Receptor 1
Acetylcholinesterase 1
Acetylcholines 7
Dopamines 7
Sarins 2
Cocaines 2
Propofols 2
Nicotines 2
ADP and Pi 1
Potassium Ions 30
Chloride Ions 12
Sodium Ions 30
Calcium Ions 8

















Please allot approximately 60 minutes to put together your first kit and 45 minutes for each additional kit (if you have more than one).

Synapse Construction Kit© Contents and Assembly

Find information about the contents of your Synapse Construction Kit© and directions for assembling the pieces from 3D Molecular Designs.


Synapse Construction Kit© Neurotransmission and Perturbance

Have your students model the events of neurotransmission at a cholinergic, dopaminergic and/or GABAergic synapse. Then, model a perturbance in a cholinergic, dopaminergic and/or GABAergic synapse.


Synapse Construction Kit© Teacher Notes

This activity guide will help you consider different ways you can use the Synapse Construction Kit©. We encourage you to modify these lessons and activities to meet the learning objectives and needs of your specific students.


Synapse Construction Kit© Videos

Explore videos to enhance your use of 3D Molecular Designs' Synapse Construction Kit© and classroom study of neurons and synapses.


Synapse Construction Kit© Neuronal Synapse Guides

Introduce your students to dopaminergic, cholinergic and/or GABAergic neuronal synapses with 3D Molecular Designs' Synapse Construction Kit©.


Synapse Construction Kit© Next Generation Science Standards

Synapse Construction Kit© Connections to: A Framework for K-12 Science Education Practices, Crosscutting Concepts, and Core Ideas


Synapse Construction Kit© Resting and Action Potentials

Set up axonal membranes and model neuronal resting potential and action potential with the Synapse Construction Kit© from 3D Molecular Designs.


Product Details


Grade Level

High School

Students per Group



Choking Hazard
Science Education Product
California Proposition 65

List Price

Synapse Construction Kit©
    $129 (SCK-01)
    $375 (SCK-03)
    $715 (SCK-06)

Disinfecting Kits

Teacher Tips

Assemble kit(s) on poster board or a large piece of cardboard to make transportation easier.

Assemble kit(s) on a large dry erase board or butcher paper so students can draw additional pieces.

Colors may fade. Consider storing foam kits in a dark location such as a closet, cabinet or drawer.

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