Human SPR mRNA Gene Map© Connections to: A Framework for K-12 Science Education Practices, Crosscutting Concepts, and Core Ideas*

Dimension 1: Scientific and Engineering Practices

1. Asking questions (for science) and defining problems (for engineering)
2. Developing and using models
4. Analyzing and interpreting data
6. Constructing explanations (for science) and designing solutions (for engineering)

Dimension 2: Crosscutting Concepts

1. Patterns
2. Cause and effect: Mechanism and explanation
4. Systems and system models
6. Structure and function
7. Stability and change

Dimension 3: Disciplinary Core Ideas

Physical Science

HS-PS 1: Matter and its Interactions

HS-PS 1-6: Refine the design of a chemical system by specifying a change in conditions that would produce increased amounts of products at equilibrium

Life Science

HS-LS 1: From Molecules to Organisms: Structures and Processes

HS-LS 1-1: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells
HS-LS 1-2: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms

HS-LS 3: Heredity: Inheritance and Variation of Traits

HS-LS 3-1: Ask questions to clarify relationship about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring

Engineering, Technology and Application of Science

HS-ETS 1: Engineering Design

HS-ETS 1-2: Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering
HS-ETS 1-3: Evaluate a solution to a complex real-world problem based on prioritized criteria and tradeoffs that account for a range of constraints, including cost, safety, reliability and aesthetics, as well as possible social, cultural, and environmental impacts

HS-ETS 2: Links Among Engineering, Technology, Science, and Society

ETS 2.A: Interdependence of Science, Engineering, and Technology
ETS 2.B: Influence of Engineering, Technology, and Science on Society and the Natural World


*The NSTA Reader’s Guide to A Framework for K-12 Science Education, National Research Council (NRC), 2011. A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas. Washington, D.C.: National Academies Press.