Substrate Specificity Kit© Teacher Resources

 

Students can use the Substrate Specificity Kit© to:

  • Use color-coded functional groups to construct a substrate and examine its chemical properties.
  • Use a mini toober to engineer an enzyme active site specific to the substrate constructed.
  • Explore different types of specificity including stereochemical specificity and absolute specificity.
  • Discover how subtle changes in enzyme structure can potentially have a significant impact on substrate binding in the active site.

Substrate Specificity Kit Contents and Assembly

Find information about the contents of your Substrate Specificity Kit© and directions for assembling the pieces so you and your students can start exploring the highly specific interaction between substrates and enzymes.

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Substrate Specificity Kit© 3-Foot Mini Toober Activity Student Handout and Key

The 3-Foot Mini Toober Activity shows students, through modeling, how even a slight change in the shape of either the substrate or the enzyme may alter the efficient and selective ability of the enzyme to catalyze the reaction.

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Substrate Specificity Kit Teacher Notes

This activity guide will help you consider different ways you may use these materials. We encourage you to modify these lessons and activities to meet the learning objectives and needs of your specific students.

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Substrate Specificity Kit© Next Generation Science Standards

Substrate Specificity Kit Connections to: A Framework for K-12 Science Education Practices, Crosscutting Concepts, and Core Ideas

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Substrate Specificity Kit© 6-Foot Mini Toober Activity Student Handout and Key

The 6-Foot Mini Toober Activity shows students, through modeling, how even a slight change in the shape of either the substrate or the enzyme may alter the efficient and selective ability of the enzyme to catalyze the reaction.

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