Our colorful, 3D mini model of ATP synthase will help your students better understand this important enzyme that provides energy for the cell. ATP synthase is a multi-subunit protein complex embedded in the inner membrane of mitochondria. The protein gradient that builds up across this membrane drives the rotation of the F0 complex and its associated gamma subunit in such a way that the F1 complex produces ATP – the universal currency of energy. READ MORE
3D Molecular Designs' founder, Tim Herman, PhD, explores in a guest blog for Addgene Plasmid Repository why we need physical models of protein structure, how educators and students use molecular models, and how researchers use physical models of protein structure.
Incorporate the concepts of protein structure and function while teaching the immune system using our antibody model – now printed in more durable plastic. Antibodies are composed of 12 repeating immunoglobulin folds. Our model highlights the four polypeptides – two yellow heavy chains and two red light chains – that join to form the iconic “Y” shaped molecule. Students will model how an antibody binds to two antigens (purple globular structures) found on an influenza virus protein.
Use the Antibody and Antigen Models to actively simulate the antibody binding and specificity illustrated in our Flu Fight: Immunity & Infection Panorama!
The hormone insulin is an important regulatory protein that helps control blood sugar levels by signaling cells to take up glucose circulating in the blood. Our model, now printed in more durable plastic, features a 51-amino acid peptide with a longer B chain (colored orange) composed of an alpha helix and a beta strand, and a shorter A chain (colored purple) consisting of two alpha helices. The two chains are linked together by three disulfide bonds formed between the three pairs of cysteine side chains displayed in the model. READ MORE
Use the Insulin Model as an accurate smaller scale template when using our Insulin mRNA to Protein Kit.
The Science Olympiad Protein Modeling Event will return to the National Science Olympiad Tournament in 2019. The event does continue again this year as a featured trial event, focusing on two proteins found on the surface of the influenza virus: hemagglutinin and neuraminidase. Pre-Build Kits, Practice Kits and other materials are available for purchase. READ MORE
Engage your classroom with hands-on modeling of neuronal communication using the colorful foam pieces in our new Synapse Construction Kit! READ MORE
Flu Fight: Immunity & Infection is a stunning watercolor poster by scientist, author and artist David Goodsell, PhD, that explores the molecular Editmechanisms that protect our bodies from influenza virus infection, and the events that transpire when those defenses fail and infection occurs. READ MORE
David Goodsell Featured in Video
Congratulations to Dr. Goodsell on a recent video profile of him and his landscapes, which accurately illustrate the size, shape, and distribution of proteins in their natural environment of the cell. These unique water color images connect the molecular world, inferred by X-ray crystallography and NMR spectroscopy, with the cellular world, observed by light and electron microscopy.